Just adding a link and text of NCSoft's support page about click to move for posterity:
https://help.ncsoft.com/app/answers/detail/a_id/3141/~/click-to-move-in-city-of-heroes
Click-to-Move in City of Heroes Answer ID 3141 | Published 10/17/2005 12:16 PM | Updated 12/10/2012 09:06 AM
Can my character travel without the use of a keyboard?
Players have the ability to move their characters simply by using the mouse. This feature is disabled by default, so here is how to enable it.
Click on Menu, then Options. Under the Controls tab, you will see Click-To-Move under the Mouse section. Click on Disabled and it will change to Enabled.
Click to move image
With this feature on, you can left click on a target point (or object) and your character will move to that point. Double-click on a target to move to it and interact with it. You can go to a door and walk through, move to an NPC (non-player character) and begin talking, etc.
On-Demand Use: You can hold down a key (default is V) to temporarily enable the feature for as long as the key is held. If the feature is set to run all the time, holding down the key will temporarily disable click to move.
Autorun: Hold down both the left and right mouse buttons for two seconds to enable autorun. Hold down these buttons again to turn autorun off.
Macro commands:
/clicktomove (or /ctm ) — Turns on "Click-To-Move" /ctm_toggle 0/1 — Use 0 to toggle it on, 1 to turn it off
Felderburg 18:15, 12 August 2013 (UTC)